Gifford Bioscience is a laboratory-based contract research organisation (CRO) specializing in receptor-ligand interactions.

We undertake fee-for-service radioligand binding assays, functional assays, receptor occupancy studies, autoradiography and SPR. We support pharma companies, biotechs and university researchers around the globe.

At Gifford Bioscience, we use “gold standard” radiometric methods, fluorescence detection and label-free, kinetic affinity techniques. Our assays employ human and animal tissues, cultured cells, membranes and recombinant proteins. We are a specialized company, with expertise built up from many years of running in vitro and ex vivo ligand binding projects. Our principal investigators and scientists use this experience in collaborating with you, in assay design and in solving key issues.

Determination of receptor affinities and binding parameters for test compounds in a tissue homogenate or cell preparation.

Measurement of second messenger levels. Determination of potency and efficacy of compounds and identification of agonists and antagonists.

Imaging distribution of a labeled test drug in tissue or organ sections.

Kinetic, label-fee measurement of a drug’s affinity for its receptor using Surface Plasmon Resonance (SPR).

Measurement of the degree to which a test compound engages its target receptor in live cells, tissues or in an animal.

Measurement of a compounds transport into cells or efflux from cells. Determination of a compound’s potency and efficacy.

Additional Services

as part of a core receptor pharmacology study

Ancillary Services

as part of a core receptor pharmacology study

Custom Radiolabeling

Human and Animal Tissue

ELISAs

Cell Culture & Transfections

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Who We Are

Since 2017, we have been building our reputation as the experts in receptor ligand binding.

88% recurring customers

50% from USA
25% EU

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    Copyright © 2023 Gifford Bioscience Limited
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    Copyright © 2023 Gifford Bioscience Limited
    Privacy Policy