Gifford Bioscience is a laboratory-based contract research organisation (CRO) specializing in receptor-ligand interactions.
We undertake fee-for-service radioligand binding assays, functional assays, receptor occupancy studies, autoradiography and SPR. We support pharma companies, biotechs and university researchers around the globe.
At Gifford Bioscience, we use “gold standard” radiometric methods, fluorescence detection and label-free, kinetic affinity techniques. Our assays employ human and animal tissues, cultured cells, membranes and recombinant proteins. We are a specialized company, with expertise built up from many years of running in vitro and ex vivo ligand binding projects. Our principal investigators and scientists use this experience in collaborating with you, in assay design and in solving key issues.
Determination of receptor affinities and binding parameters for test compounds in a tissue homogenate or cell preparation.
Measurement of second messenger levels. Determination of potency and efficacy of compounds and identification of agonists and antagonists.
Kinetic, label-fee measurement of a drug’s affinity for its receptor using Surface Plasmon Resonance (SPR).
Measurement of the degree to which a test compound engages its target receptor in live cells, tissues or in an animal.
Measurement of a compounds transport into cells or efflux from cells. Determination of a compound’s potency and efficacy.
Additional Services
as part of a core receptor pharmacology study
Ancillary Services
as part of a core receptor pharmacology study
Custom Radiolabeling
Human and Animal Tissue
ELISAs
Cell Culture & Transfections
Latest News
ELRIG 2023 – We’re Exhibiting
Gifford Bioscience will be exhibiting at this year's ELRIG – Drug Discovery meeting in Liverpool on the 18th and...
Download Our Latest Price Guide
We have updated our price guide, adding further tables for our standard assays and new tiers for volume discounts....
Our New Principal Investigator, Dr Sarah Routledge
Sarah joined Gifford Bioscience in 2021, following 10 years of post-doctoral research at the Universities of...
Who We Are
88% recurring customers
50% from USA
25% EU
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