Gifford Bioscience is a laboratory-based contract research organisation (CRO), specializing in ligand binding and receptor occupancy assays.

We undertake fee-for-service radioligand binding assays, functional assays, receptor occupancy studies, autoradiography and SPR. We support pharma companies, biotechs and university researchers around the globe.

At Gifford Bioscience, we use “gold standard” radiometric methods, fluorescence detection and label-free, kinetic affinity techniques. For our assays, we employ human and animal tissues, cultured cells, membranes and recombinant proteins. We are a specialized company, with expertise built up from many years of running in vitro and ex vivo ligand binding projects. Our principal investigators and scientists use this experience in full collaboration with our customers: from assay design, to solving key issues, to interpreting the results. CONTACT US for a chat.

Determination of receptor affinities and ligand binding parameters for test compounds in a tissue homogenate or cell preparation.

Measurement of second messenger levels resulting from ligand binding. Determination of potency and efficacy of compounds and identification of agonists and antagonists.

Imaging the distribution of a labeled test drug in tissue sections. Quantification of ligand binding in regions of interest.

Kinetic, label-fee measurement of a drug’s affinity for its receptor using Surface Plasmon Resonance (SPR).

Measurement of the degree to which a test compound engages its target receptor in tissues or in an animal.

Measurement of a compounds transport into cells or efflux from cells. Determination of a compound’s potency and efficacy.

Additional Services

as part of a core receptor pharmacology study

Ancillary Services

as part of a core receptor pharmacology study

Custom Radiolabeling

Human and Animal Tissue


Cell Culture & Transfections

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Who We Are

Since 2017, we have been building our reputation as the experts in receptor ligand binding.

88% recurring customers

50% from USA
25% EU

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Copyright © 2024 Gifford Bioscience Limited
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Copyright © 2024 Gifford Bioscience Limited
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